Massiever loss of performance at 3.6

Hello people, I'm new here and have a problem with my v8. don't really know what that could be...

A few days ago I drove with him on the highway and suddenly realized that the water temperature was getting hotter and that he was in power. I drove out the next exit and discovered that the cooler hose had cracked and so cymbal the whole cool liquid ran out.

have replaced the hose and cleaned up new water. when I start the engine he runs in standing calmly, as normal. even if I slowly gave out, you don't notice any difference. only if I stand and give full weight while driving he first takes such a second no gazing at, in there was one or more misfires, and then accelerates quite timidly with half power....
Can someone tell me what that could be?
have already renewed the filters, the lambda probe and the spark plugs...
I am grateful for every answer